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The Influence of Liver Dysfunction on Cyclosporine Pharmacokinetics —A Comparison between 70 per cent Hepatectomy and Complete Bile Duct Ligation in Dogs—

The influence of experimentally induced hepatic dysfunction on the pharmacokinetics of Cyclosporine A (CsA) was determined in dogs. The pharmacokinetics of oral (PO) and intravenous (IV) CsA were studied before and after 70 per cent hepatectomy or complete bile duct ligation (CBDL). Changes in liver...

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Main Authors: Takaya, Shunichi, Iwatsuki, Shunzaburo, Noguchi, Takashi, Koie, Hisaaki, Zaghloul, Iman, Venkataramanan, Raman, Starzl, Thomas E.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1989
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988433/
https://ncbi.nlm.nih.gov/pubmed/2733278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/BF02471566
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