THE EFFECT OF BILE DUCT LIGATION AND BILE DIVERSION ON FK506 PHARMACOKINETICS IN DOGS

Mongrel or beagle dogs were submitted to bile duct ligation, or to extraenteric biliary diversion by means of choledochoureterostomy. The kinetics of intravenously administered FK506 was not changed from control status two weeks after bile duct ligation, but the bioavailability of orally administere...

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Main Authors: Furukawa, Hiroyoki, Imventarza, Oscar, Venkataramanan, Raman, Suzuki, Masatoshi, Zhu, Yue, Warty, Vijay S., Fung, John, Todo, Satoru, Starzl, Thomas E.
Format: Artigo
Jezik:Inglês
Izdano: 1992
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091377/
https://ncbi.nlm.nih.gov/pubmed/1373531
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