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Hydrogen Peroxide Removes TRPM4 Current Desensitization Conferring Increased Vulnerability to Necrotic Cell Death

Necrosis is associated with an increase in plasma membrane permeability, cell swelling, and loss of membrane integrity with subsequent release of cytoplasmic constituents. Severe redox imbalance by overproduction of reactive oxygen species is one of the main causes of necrosis. Here we demonstrate t...

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Detalhes bibliográficos
Main Authors: Simon, Felipe, Leiva-Salcedo, Elías, Armisén, Ricardo, Riveros, Ana, Cerda, Oscar, Varela, Diego, Eguiguren, Ana Luisa, Olivero, Pablo, Stutzin, Andrés
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988321/
https://ncbi.nlm.nih.gov/pubmed/20884614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.155390
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