Hydrogen Peroxide Removes TRPM4 Current Desensitization Conferring Increased Vulnerability to Necrotic Cell Death

Necrosis is associated with an increase in plasma membrane permeability, cell swelling, and loss of membrane integrity with subsequent release of cytoplasmic constituents. Severe redox imbalance by overproduction of reactive oxygen species is one of the main causes of necrosis. Here we demonstrate t...

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Главные авторы: Simon, Felipe, Leiva-Salcedo, Elías, Armisén, Ricardo, Riveros, Ana, Cerda, Oscar, Varela, Diego, Eguiguren, Ana Luisa, Olivero, Pablo, Stutzin, Andrés
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2010
Предметы:
Cell Biology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988321/
https://ncbi.nlm.nih.gov/pubmed/20884614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.155390
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