A Phase I and Biology Study of Gefitinib and Radiation in Children with Newly Diagnosed Brain Stem Gliomas or Supratentorial Malignant Gliomas

PURPOSE: To estimate the maximum tolerated dose (MTD); study the pharmacology of escalating doses of gefitinib combined with radiation therapy in patients ≤21 years with newly diagnosed intrinsic brainstem gliomas (BSG) and incompletely resected supratentorial malignant gliomas (STMG); and to invest...

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Bibliografski detalji
Glavni autori: Geyer, J. Russell, Stewart, Clinton F., Kocak, Mehmet, Broniscer, Alberto, Phillips, Peter, Douglas, James G., Blaney, Susan M., Packer, Roger J., Gururangan, Sri, Banerjee, Anu, Kieran, Mark W., Kun, Larry E., Gilbertson, Richard J., Boyett, James M.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988095/
https://ncbi.nlm.nih.gov/pubmed/20708924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejca.2010.07.005
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