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Comparison of anti-CD3 and anti-CD28-coated beads with soluble anti-CD3 for expanding human T cells: Differing impact on CD8 T cell phenotype and responsiveness to restimulation

BACKGROUND: The ability to expand virus- or tumor-specific T cells without damaging their functional capabilities is critical for success adoptive transfer immunotherapy of patients with opportunistic infection or tumor. Careful comparisons can help identify expansion methods better suited for parti...

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Detalhes bibliográficos
Main Authors: Li, Yixin, Kurlander, Roger J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2987859/
https://ncbi.nlm.nih.gov/pubmed/20977748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-8-104
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