Mismatch Repair–Independent Increase in Spontaneous Mutagenesis in Yeast Lacking Non-Essential Subunits of DNA Polymerase ε

Yeast DNA polymerase ε (Pol ε) is a highly accurate and processive enzyme that participates in nuclear DNA replication of the leading strand template. In addition to a large subunit (Pol2) harboring the polymerase and proofreading exonuclease active sites, Pol ε also has one essential subunit (Dpb2)...

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Detalhes bibliográficos
Main Authors: Aksenova, Anna, Volkov, Kirill, Maceluch, Jaroslaw, Pursell, Zachary F., Rogozin, Igor B., Kunkel, Thomas A., Pavlov, Youri I., Johansson, Erik
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2987839/
https://ncbi.nlm.nih.gov/pubmed/21124948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001209
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