Comparison of the pharmacokinetics, safety and tolerability of two concentrations of a new liquid recombinant human growth hormone formulation versus the freeze-dried formulation

BACKGROUND: Somatropin is recombinant human growth hormone (GH) used for the treatment of growth failure in children and GH deficiency in adults. Two concentrations of a liquid formulation have been developed: 5.83 and 8.0 mg/mL. This trial compared the pharmacokinetics (PK), safety and tolerability...

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Hauptverfasser: Liedert, Bernd, Forssmann, Ulf, Wolna, Peter, Golob, Michaela, Kovar, Andreas
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2987775/
https://ncbi.nlm.nih.gov/pubmed/20961422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6904-10-14
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