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Regulation of Ack1 localization and activity by the amino-terminal SAM domain
BACKGROUND: The mechanisms that regulate the activity of the nonreceptor tyrosine kinase Ack1 (activated Cdc42-associated kinase) are poorly understood. The amino-terminal region of Ack1 is predicted to contain a sterile alpha motif (SAM) domain. SAM domains share a common fold and mediate protein-p...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2987765/ https://ncbi.nlm.nih.gov/pubmed/20979614 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-11-42 |
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