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Regulation of Ack1 localization and activity by the amino-terminal SAM domain

BACKGROUND: The mechanisms that regulate the activity of the nonreceptor tyrosine kinase Ack1 (activated Cdc42-associated kinase) are poorly understood. The amino-terminal region of Ack1 is predicted to contain a sterile alpha motif (SAM) domain. SAM domains share a common fold and mediate protein-p...

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Detalhes bibliográficos
Main Authors: Prieto-Echagüe, Victoria, Gucwa, Azad, Brown, Deborah A, Miller, W Todd
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2987765/
https://ncbi.nlm.nih.gov/pubmed/20979614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-11-42
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