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Cancer-associated Mutations Activate the Nonreceptor Tyrosine Kinase Ack1
Ack1 is a nonreceptor tyrosine kinase that participates in tumorigenesis, cell survival, and migration. Relatively little is known about the mechanisms that regulate Ack1 activity. Recently, four somatic missense mutations of Ack1 were identified in cancer tissue samples, but the effects on Ack1 act...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2856269/ https://ncbi.nlm.nih.gov/pubmed/20110370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.060459 |
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