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Effects of the TLR2 Agonists MALP-2 and Pam(3)Cys in Isolated Mouse Lungs

BACKGROUND: Gram-positive and Gram-negative bacteria are main causes of pneumonia or acute lung injury. They are recognized by the innate immune system via toll-like receptor-2 (TLR2) or TLR4, respectively. Among all organs, the lungs have the highest expression of TLR2 receptors, but little is know...

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Autors principals: Barrenschee, Martina, Lex, Dennis, Uhlig, Stefan
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2987752/
https://ncbi.nlm.nih.gov/pubmed/21124967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013889
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