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General Approach to Epipolythiodiketopiperazine Alkaloids: Total Synthesis of (+)-Chaetocins A, C and (+)-12,12′-Dideoxychetracin A

A highly stereoselective and systematic strategy for the introduction of polysulfides in the synthesis of epipolythiodiketopiperazines is described. We report the first total synthesis of dimeric epitri- and epitetrathiodiketopiperazines.

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Detalhes bibliográficos
Main Authors: Kim, Justin, Movassaghi, Mohammad
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2987664/
https://ncbi.nlm.nih.gov/pubmed/20866039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja106869s
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