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Dopaminergic modulation of axon initial segment calcium channels regulates action potential initiation

Action potentials initiate in the axon initial segment (AIS), a specialized compartment enriched with Na(+) and K(+) channels. Recently, we found that T- and R-type Ca(2+) channels are concentrated in the AIS, where they contribute to local subthreshold membrane depolarization and thereby influence...

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Auteurs principaux: Bender, Kevin J., Ford, Christopher P., Trussell, Laurence O.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2987607/
https://ncbi.nlm.nih.gov/pubmed/21040850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2010.09.026
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