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Dopaminergic modulation of axon initial segment calcium channels regulates action potential initiation
Action potentials initiate in the axon initial segment (AIS), a specialized compartment enriched with Na(+) and K(+) channels. Recently, we found that T- and R-type Ca(2+) channels are concentrated in the AIS, where they contribute to local subthreshold membrane depolarization and thereby influence...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2987607/ https://ncbi.nlm.nih.gov/pubmed/21040850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2010.09.026 |
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