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Competition for self ligands restrains homeostatic proliferation of naive CD4 T cells
T cell antigen receptor (TCR) diversity is a critical feature of adaptive immunity. However, restriction of TCR diversity is a potential risk during immune reconstitution by homeostatic proliferation. What peripheral mechanisms are in place to maintain TCR diversity during recovery from lymphopenia?...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The National Academy of Sciences
2003
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC298748/ https://ncbi.nlm.nih.gov/pubmed/12525694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0334572100 |
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