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Co-expression of FBN1 with mesenchyme-specific genes in mouse cell lines: implications for phenotypic variability in Marfan syndrome

Mutations in the human FBN1 gene cause Marfan syndrome, a complex disease affecting connective tissues but with a highly variable phenotype. To identify genes that might participate in epistatic interactions with FBN1, and could therefore explain the observed phenotypic variability, we have looked f...

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Bibliografske podrobnosti
Main Authors: Summers, Kim M, Raza, Sobia, van Nimwegen, Erik, Freeman, Thomas C, Hume, David A
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2987476/
https://ncbi.nlm.nih.gov/pubmed/20551991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2010.91
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