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A powerful score test to detect positive selection in genome-wide scans
One of the surest signatures of recent positive selection is a local elevation of advantageous allele frequency and linkage disequilibrium (LD). We proposed to detect such hitchhiking effects by using extended stretches of homozygosity as a surrogate indicator of recent positive selection. An extend...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2987455/ https://ncbi.nlm.nih.gov/pubmed/20461112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2010.60 |
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