The mouse organellar biogenesis mutant buff results from a mutation in Vps33a, a homologue of yeast vps33 and Drosophila carnation

In the mouse, more than 16 loci are associated with mutant phenotypes that include defective pigmentation, aberrant targeting of lysosomal enzymes, prolonged bleeding, and immunodeficiency, the result of defective biogenesis of cytoplasmic organelles: melanosomes, lysosomes, and various storage gran...

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Detalhes bibliográficos
Main Authors: Suzuki, Tamio, Oiso, Naoki, Gautam, Rashi, Novak, Edward K., Panthier, Jean-Jacques, Suprabha, P. G., Vida, Thomas, Swank, Richard T., Spritz, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC298741/
https://ncbi.nlm.nih.gov/pubmed/12538872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0237292100
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