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The obesity-associated SNPs in intron 1 of the FTO gene affect primary transcript levels

As shown by genome-wide association studies single-nucleotide polymorphisms (SNPs) within intron 1 of the FTO gene are associated with the body mass index and type II diabetes, although the functional significance of these SNPs has remained unclear. Using primer extension assays, we have determined...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Berulava, Tea, Horsthemke, Bernhard
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2987405/
https://ncbi.nlm.nih.gov/pubmed/20512162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2010.71
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