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Stabilization of perfect and imperfect tandem repeats by single-strand DNA exonucleases

Rearrangements between tandemly repeated DNA sequences are a common source of genetic instability. Such rearrangements underlie several human genetic diseases. In many organisms, the mismatch-repair (MMR) system functions to stabilize repeats when the repeat unit is short or when sequence imperfecti...

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Bibliografske podrobnosti
Main Authors: Feschenko, Vladimir V., Rajman, Luis A., Lovett, Susan T.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 2003
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC298739/
https://ncbi.nlm.nih.gov/pubmed/12538867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0233122100
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