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Stabilization of perfect and imperfect tandem repeats by single-strand DNA exonucleases
Rearrangements between tandemly repeated DNA sequences are a common source of genetic instability. Such rearrangements underlie several human genetic diseases. In many organisms, the mismatch-repair (MMR) system functions to stabilize repeats when the repeat unit is short or when sequence imperfecti...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The National Academy of Sciences
2003
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC298739/ https://ncbi.nlm.nih.gov/pubmed/12538867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0233122100 |
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