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Polymorphisms in the IL2, IL2RA and IL2RB genes in multiple sclerosis risk
Interleukin (IL)-2/IL-2R signalling promotes proliferation and survival of activated T cells and has an essential non-redundant role in the production of regulatory T cells. Associations with different autoimmune diseases of polymorphisms in a linkage disequilibrium block in which the IL2/IL21 genes...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2010
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2987360/ https://ncbi.nlm.nih.gov/pubmed/20179739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2010.15 |
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