Polymorphisms in the IL2, IL2RA and IL2RB genes in multiple sclerosis risk

Interleukin (IL)-2/IL-2R signalling promotes proliferation and survival of activated T cells and has an essential non-redundant role in the production of regulatory T cells. Associations with different autoimmune diseases of polymorphisms in a linkage disequilibrium block in which the IL2/IL21 genes...

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Autores principales: Cavanillas, María L, Alcina, Antonio, Núñez, Concepción, de las Heras, Virginia, Fernández-Arquero, Miguel, Bartolomé, Manuel, de la Concha, Emilio G, Fernández, Oscar, Arroyo, Rafael, Matesanz, Fuencisla, Urcelay, Elena
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2987360/
https://ncbi.nlm.nih.gov/pubmed/20179739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2010.15
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