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Vaccinia Virus Blocks Stat1-Dependent and Stat1-Independent Gene Expression Induced by Type I and Type II Interferons

Blocking the function of Stat (signal transducer and activator of transcription) proteins, which are critical for antiviral responses, has evolved as a common mechanism for pathogen immune evasion. The poxvirus-encoded phosphatase H1 is critical for viral replication, and may play an additional role...

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Bibliographic Details
Main Authors: Mann, Brandon A., Huang, Julia He, Li, Ping, Chang, Hua-Chen, Slee, Roger B., O'Sullivan, Audrey, Mathur, Anita, Yeh, Norman, Klemsz, Michael J., Brutkiewicz, Randy R., Blum, Janice S., Kaplan, Mark H.
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2987269/
https://ncbi.nlm.nih.gov/pubmed/18593332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jir.2007.0113
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