A rare variant of the TYK2 gene is confirmed to be associated with multiple sclerosis

A rare functional variant within the TYK2 gene (rs34536443) has been reported as protective in multiple sclerosis (MS) in recent studies. However, because of the low frequency of the minor allele (minor allele frequency=0.04), genome-wide significant association has been hard to establish. We genoty...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Mero, Inger-Lise, Lorentzen, Åslaug R, Ban, Maria, Smestad, Cathrine, Celius, Elisabeth G, Aarseth, Jan H, Myhr, Kjell-Morten, Link, Jenny, Hillert, Jan, Olsson, Tomas, Kockum, Ingrid, Masterman, Thomas, Oturai, Annette Bang, Søndergaard, Helle Bach, Sellebjerg, Finn, Saarela, Janna, Kemppinen, Anu, Elovaara, Irina, Spurkland, Anne, Dudbridge, Frank, Lie, Benedicte A, Harbo, Hanne F
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2010
Materias:
Short Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2987240/
https://ncbi.nlm.nih.gov/pubmed/19888296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2009.195
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares