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Polymorphisms in TLR4 and TLR2 genes, cytokine production and survival in rural Ghana

Toll-like receptors (TLRs) are involved in the induction of an adequate immune response on infection. We hypothesized that genetic variation in TLR4 and TLR2 genes could influence this response and lead to variability in cytokine production and survival. We tested this hypothesis in 4292 participant...

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Detalhes bibliográficos
Main Authors: May, Linda, van Bodegom, David, Frölich, Marijke, van Lieshout, Lisette, Slagboom, P Eline, Westendorp, Rudi GJ, Kuningas, Maris
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2987239/
https://ncbi.nlm.nih.gov/pubmed/19844258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2009.182
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