Selection for Genetic Variation Inducing Pro-Inflammatory Responses under Adverse Environmental Conditions in a Ghanaian Population

BACKGROUND: Chronic inflammation is involved in the pathogenesis of chronic age-associated, degenerative diseases. Pro-inflammatory host responses that are deleterious later in life may originate from evolutionary selection for genetic variation mediating resistance to infectious diseases under adve...

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Detalhes bibliográficos
Main Authors: Kuningas, Maris, May, Linda, Tamm, Riin, van Bodegom, David, van den Biggelaar, Anita H. J., Meij, Johannes J., Frölich, Marijke, Ziem, Juventus B., Suchiman, Helena E. D., Metspalu, Andres, Slagboom, P. Eline, Westendorp, Rudi G. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771352/
https://ncbi.nlm.nih.gov/pubmed/19907653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007795
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