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Biochemical characterization of the Yersinia YopT protease: Cleavage site and recognition elements in Rho GTPases

The Gram-negative bacterial pathogen Yersinia delivers six effector proteins into the host cells to thwart the host innate immune response. One of the effectors, YopT, causes the disruption of the actin cytoskeleton and contributes to the inhibition of phagocytosis of the pathogen. YopT functions as...

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Auteurs principaux: Shao, Feng, Vacratsis, Panayiotis O., Bao, Zhaoqin, Bowers, Katherine E., Fierke, Carol A., Dixon, Jack E.
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 2003
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC298699/
https://ncbi.nlm.nih.gov/pubmed/12538863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.252770599
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