Biochemical characterization of the Yersinia YopT protease: Cleavage site and recognition elements in Rho GTPases

The Gram-negative bacterial pathogen Yersinia delivers six effector proteins into the host cells to thwart the host innate immune response. One of the effectors, YopT, causes the disruption of the actin cytoskeleton and contributes to the inhibition of phagocytosis of the pathogen. YopT functions as...

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Bibliografske podrobnosti
Main Authors: Shao, Feng, Vacratsis, Panayiotis O., Bao, Zhaoqin, Bowers, Katherine E., Fierke, Carol A., Dixon, Jack E.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 2003
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC298699/
https://ncbi.nlm.nih.gov/pubmed/12538863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.252770599
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