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Structure of the large FK506-binding protein FKBP51, an Hsp90-binding protein and a component of steroid receptor complexes

The ability to bind immunosuppressive drugs such as cyclosporin and FK506 defines the immunophilin family of proteins, and the FK506-binding proteins form the FKBP subfamily of immunophilins. Some FKBPs, notably FKBP12 (the 12-kDa FK506-binding protein), have defined roles in regulating ion channels...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sinars, Cindy R., Cheung-Flynn, Joyce, Rimerman, Ronald A., Scammell, Jonathan G., Smith, David F., Clardy, Jon
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC298693/
https://ncbi.nlm.nih.gov/pubmed/12538866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0231020100
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