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Reactivity-based one-pot total synthesis of fucose GM(1) oligosaccharide: A sialylated antigenic epitope of small-cell lung cancer
The total synthesis of the sialic acid-containing antigenic epitope fucose GM(1) (Fuc-GM(1)) by an improved reactivity-based one-pot synthetic strategy is reported. Based on a thioglycoside reactivity database, three saccharide building blocks, 3, 4, and 5, were designed and prepared to incorporate...
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| Główni autorzy: | , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
The National Academy of Sciences
2003
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC298681/ https://ncbi.nlm.nih.gov/pubmed/12552090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0337590100 |
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