HLA-DR4 subtype frequencies in rheumatoid arthritis indicate that DRB1 is the major susceptibility locus within the HLA class II region.

Susceptibility to rheumatoid arthritis (RA) may be due to the presence of shared functional epitopes common to the HLA-DR beta chains of several RA-associated haplotypes. We have obtained direct evidence for this hypothesis by using the polymerase chain reaction and sequencing the DRB1 and DQB1 gene...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wordsworth, B P, Lanchbury, J S, Sakkas, L I, Welsh, K I, Panayi, G S, Bell, J I
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1989
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC298641/
https://ncbi.nlm.nih.gov/pubmed/2481309
Etiketak: Etiketa erantsi
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