Peripheral tolerance to allogeneic class II histocompatibility antigens expressed in transgenic mice: evidence against a clonal-deletion mechanism.

To examine the effects of aberrant expression of class II major histocompatibility complex (MHC) proteins on tolerance development, transgenic mice expressing the I-Ad genes under control of the pancreatic elastase promoter were produced. Such transgenic mice express I-Ad exclusively on exocrine pan...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Murphy, K M, Weaver, C T, Elish, M, Allen, P M, Loh, D Y
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1989
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298638/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2513571/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.24.10034
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