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Peripheral tolerance to allogeneic class II histocompatibility antigens expressed in transgenic mice: evidence against a clonal-deletion mechanism.

To examine the effects of aberrant expression of class II major histocompatibility complex (MHC) proteins on tolerance development, transgenic mice expressing the I-Ad genes under control of the pancreatic elastase promoter were produced. Such transgenic mice express I-Ad exclusively on exocrine pan...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Murphy, K M, Weaver, C T, Elish, M, Allen, P M, Loh, D Y
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298638/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2513571/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.24.10034
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