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Identification of the binding domain for NADP+ of human glucose-6-phosphate dehydrogenase by sequence analysis of mutants.

Human erythrocyte glucose-6-phosphate dehydrogenase is normally quite stable in the presence of 10 microM NADP+. Certain glucose-6-phosphate dehydrogenase variants lose virtually all their activity at this concentration of NADP+ but are reactivated by 200 microM NADP+. Such variants presumably have...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Hirono, A, Kuhl, W, Gelbart, T, Forman, L, Fairbanks, V F, Beutler, E
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1989
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298633/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2602358/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.24.10015
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