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Construction of human chromosome 21-specific yeast artificial chromosomes.

Chromosome 21-specific yeast artificial chromosomes (YACs) have been constructed by a method that performs all steps in agarose, allowing size selection by pulsed-field gel electrophoresis and the use of nanogram to microgram quantities of DNA. The DNA sources used were hybrid cell line WAV-17, cont...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: McCormick, M K, Shero, J H, Cheung, M C, Kan, Y W, Hieter, P A, Antonarakis, S E
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298628/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2690083/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.24.9991
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