Construction of human chromosome 21-specific yeast artificial chromosomes.

Chromosome 21-specific yeast artificial chromosomes (YACs) have been constructed by a method that performs all steps in agarose, allowing size selection by pulsed-field gel electrophoresis and the use of nanogram to microgram quantities of DNA. The DNA sources used were hybrid cell line WAV-17, cont...

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Autori principali: McCormick, M K, Shero, J H, Cheung, M C, Kan, Y W, Hieter, P A, Antonarakis, S E
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1989
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC298628/
https://ncbi.nlm.nih.gov/pubmed/2690083
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