H1 haplotype of the MAPT gene is associated with lower regional gray matter volume in healthy carriers

The microtubule-associated protein Tau (MAPT) gene codes for the protein Tau that is involved in the pathogenesis of neurodegenerative diseases. Recent studies have detected an over-representation of the H1 haplotype of the MAPT gene in neurodegenerative disorders such as progressive supranuclear pa...

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Detalhes bibliográficos
Main Authors: Canu, Elisa, Boccardi, Marina, Ghidoni, Roberta, Benussi, Luisa, Testa, Cristina, Pievani, Michela, Bonetti, Matteo, Binetti, Giuliano, Frisoni, Giovanni B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2986165/
https://ncbi.nlm.nih.gov/pubmed/18854867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2008.185
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