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STAT3 single-nucleotide polymorphisms and STAT3 mutations associated with hyper-IgE syndrome are not responsible for increased serum IgE serum levels in asthma families

Mutations in STAT3 (signal transducer and activator of transcription 3) have recently been found to cause the hyper-IgE syndrome (HIES) – a rare immunodeficiency syndrome including complex somatic features. We now tested whether STAT3 mutations or single-nucleotide polymorphisms (SNPs) within STAT3...

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Autori principali: Wjst, Matthias, Lichtner, Peter, Meitinger, Thomas, Grimbacher, Bodo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2986162/
https://ncbi.nlm.nih.gov/pubmed/18841165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2008.169
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