Multiple functions of human single-stranded-DNA binding protein in simian virus 40 DNA replication: single-strand stabilization and stimulation of DNA polymerases alpha and delta.

The human single-stranded-DNA binding protein (human SSB) is required for simian virus 40 (SV40) DNA replication in vitro. SV40 large tumor antigen and human SSB can support extensive unwinding of SV40 origin-containing DNA in the presence of ATP and a topoisomerase that relieves positive superhelic...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Kenny, M K, Lee, S H, Hurwitz, J
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298580/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2557626/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.24.9757
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