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Multiple functions of human single-stranded-DNA binding protein in simian virus 40 DNA replication: single-strand stabilization and stimulation of DNA polymerases alpha and delta.

The human single-stranded-DNA binding protein (human SSB) is required for simian virus 40 (SV40) DNA replication in vitro. SV40 large tumor antigen and human SSB can support extensive unwinding of SV40 origin-containing DNA in the presence of ATP and a topoisomerase that relieves positive superhelic...

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Detalhes bibliográficos
Main Authors: Kenny, M K, Lee, S H, Hurwitz, J
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC298580/
https://ncbi.nlm.nih.gov/pubmed/2557626
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