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Purified, modified eel sodium channels are active in planar bilayers in the absence of activating neurotoxins.

A recent study showed that limited trypsin treatment of liposomes containing purified Electrophorus electricus sodium channels activates a sodium radiotracer flux. We now report that similarly treated sodium channels show voltage-gated, tetrodotoxin-sensitive and highly sodium-selective single-chann...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Shenkel, S, Cooper, E C, James, W, Agnew, W S, Sigworth, F J
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1989
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298544/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2556720/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.23.9592
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