Purified, modified eel sodium channels are active in planar bilayers in the absence of activating neurotoxins.

A recent study showed that limited trypsin treatment of liposomes containing purified Electrophorus electricus sodium channels activates a sodium radiotracer flux. We now report that similarly treated sodium channels show voltage-gated, tetrodotoxin-sensitive and highly sodium-selective single-chann...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Shenkel, S, Cooper, E C, James, W, Agnew, W S, Sigworth, F J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1989
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298544/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2556720/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.23.9592
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