Nonpsychotropic cannabinoid acts as a functional N-methyl-D-aspartate receptor blocker.

Binding studies using the enantiomers of the synthetic cannabinoid 7-hydroxy-delta 6-tetrahydrocannabinol 1,1-dimethylheptyl homolog in preparations of rat brain cortical membranes reveal that the (+)-(3S,4S) enantiomer HU-211 blocks N-methyl-D-aspartate (NMDA) receptors in a stereospecific manner a...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Feigenbaum, J J, Bergmann, F, Richmond, S A, Mechoulam, R, Nadler, V, Kloog, Y, Sokolovsky, M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1989
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298542/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2556719/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.23.9584
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