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Epstein-Barr virus nuclear protein 2 is a key determinant of lymphocyte transformation.
Epstein-Barr virus (EBV) efficiently transforms B lymphocytes to perpetual proliferation. The EBV laboratory strain P3HR-1 is transformation-incompetent and lacks a DNA segment that includes the EBV nuclear antigen 2 (EBNA-2) gene and a portion of the EBNA leader protein (EBNA-LP) gene. These two ge...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1989
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298536/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2556717/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.23.9558 |
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