Epstein-Barr virus nuclear proteins EBNA-3A and EBNA-3C are essential for B-lymphocyte growth transformation.

Recombinant Epstein-Barr viruses (EBV) with a translation termination codon mutation inserted into the nuclear protein 3A (EBNA-3A) or 3C (EBNA-3C) open reading frame were generated by second-site homologous recombination. These mutant viruses were used to infect primary B lymphocytes to assess the...

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Bibliographic Details
Published in:J Virol
Main Authors: Tomkinson, B, Robertson, E, Kieff, E
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1993
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240270/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8445720/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.4.2014-2025.1993
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