N-acetylation pharmacogenetics: a gene deletion causes absence of arylamine N-acetyltransferase in liver of slow acetylator rabbits.

The New Zealand White rabbit provides a widely used animal model for the human acetylation polymorphism, which confers marked interindividual variation in the effect and toxicity of numerous drugs, chemicals, and potential carcinogens. The relationship of a recently isolated cDNA clone, designated r...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Blum, M, Grant, D M, Demierre, A, Meyer, U A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1989
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298535/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2594784/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.23.9554
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!