Sequence of the intron/exon junctions of the coding region of the human androgen receptor gene and identification of a point mutation in a family with complete androgen insensitivity.

Androgens act through a receptor protein (AR) to mediate sex differentiation and development of the male phenotype. We have isolated the eight exons in the amino acid coding region of the AR gene from a human X chromosome library. Nucleotide sequences of the AR gene intron/exon boundaries were deter...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Lubahn, D B, Brown, T R, Simental, J A, Higgs, H N, Migeon, C J, Wilson, E M, French, F S
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1989
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298531/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2594783/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.23.9534
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