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Sequence of the intron/exon junctions of the coding region of the human androgen receptor gene and identification of a point mutation in a family with complete androgen insensitivity.

Androgens act through a receptor protein (AR) to mediate sex differentiation and development of the male phenotype. We have isolated the eight exons in the amino acid coding region of the AR gene from a human X chromosome library. Nucleotide sequences of the AR gene intron/exon boundaries were deter...

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Autori principali: Lubahn, D B, Brown, T R, Simental, J A, Higgs, H N, Migeon, C J, Wilson, E M, French, F S
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1989
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC298531/
https://ncbi.nlm.nih.gov/pubmed/2594783
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