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Positively charged amino acid residues can act as topogenic determinants in membrane proteins.

When alkaline phosphatase is fused to the periplasmic domain of a cytoplasmic membrane protein, it is efficiently exported to the periplasm. Such a hybrid protein exhibits high alkaline phosphatase enzymatic activity. When alkaline phosphatase is fused to the cytoplasmic domain of a membrane protein...

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Detalles Bibliográficos
Main Authors: Boyd, D, Beckwith, J
Formato: Artigo
Idioma:Inglês
Publicado: 1989
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC298513/
https://ncbi.nlm.nih.gov/pubmed/2594779
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