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Positively charged amino acid residues can act as topogenic determinants in membrane proteins.
When alkaline phosphatase is fused to the periplasmic domain of a cytoplasmic membrane protein, it is efficiently exported to the periplasm. Such a hybrid protein exhibits high alkaline phosphatase enzymatic activity. When alkaline phosphatase is fused to the cytoplasmic domain of a membrane protein...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1989
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298513/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2594779/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.23.9446 |
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